Phosphorylation of IRS1 at Serine 307 in Response to Insulin in Human Adipocytes Is Not Likely to be Catalyzed by p70 Ribosomal S6 Kinase

The insulin receptor substrate-1 (IRS1) is phosphorylated on serine 307 (human sequence, corresponding to murine serine 302) in response to insulin as part of a feedback loop that controls IRS1 phosphorylation on tyrosine residues by the insulin receptor. This in turn directly affects downstream sig...

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Bibliographic Details
Main Authors: Rohini Rajan, Meenu, Fagerholm, Siri, Jonsson, Cecilia, Kjölhede, Preben, Turkina, Maria, Strålfors, Peter
Format: Others
Language:English
Published: Linköpings universitet, Cellbiologi 2013
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Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-93257