The FLT3 Tyrosine Kinase in Leukemia : Deciphering the Downstream Signaling Events and Drug-Escape Mechanisms

Acute myeloid leukemia (AML) is a severe disease, which originates in blood-forming cells. Although major advances in understanding the biology of AML, the majority of patients eventually succumb to the disease. The tyrosine kinase receptor FLT3 has become an attractive therapeutic target AML for tw...

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Bibliographic Details
Main Author: Nordigården, Amanda
Format: Doctoral Thesis
Language:English
Published: Linköpings universitet, Experimentell hematologi 2013
Subjects:
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-88202
http://nbn-resolving.de/urn:isbn:978-91-7519-685-5