The FLT3 Tyrosine Kinase in Leukemia : Deciphering the Downstream Signaling Events and Drug-Escape Mechanisms
Acute myeloid leukemia (AML) is a severe disease, which originates in blood-forming cells. Although major advances in understanding the biology of AML, the majority of patients eventually succumb to the disease. The tyrosine kinase receptor FLT3 has become an attractive therapeutic target AML for tw...
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Format: | Doctoral Thesis |
Language: | English |
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Linköpings universitet, Experimentell hematologi
2013
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Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-88202 http://nbn-resolving.de/urn:isbn:978-91-7519-685-5 |