Studies on potential APC/β-catenin target genes in the Notch pathway

Studies on potential APC/β-catenin target genes in the Notch pathway

Both Notch and the Wnt pathways are key regulators in maintaining the homeostasis in the intestine. Defects on the key tumor suppressor adenomatous polyposis coli, APC a gene in the Wnt pathway is most frequently mutated in colorectal cancer. Previous studies have indicated that there is a crosstalk...

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Bibliographic Details
Main Author:	Grünberg, John
Format:	Others
Language:	English
Published:	Linköpings universitet, Institutionen för fysik, kemi och biologi 2009
Subjects:	Notch Wnt APC β-catenin Colorectal cancer HT29 LEF1/Tcf NATURAL SCIENCES NATURVETENSKAP
Online Access:	http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-18443

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