Studies on potential APC/β-catenin target genes in the Notch pathway
Both Notch and the Wnt pathways are key regulators in maintaining the homeostasis in the intestine. Defects on the key tumor suppressor adenomatous polyposis coli, APC a gene in the Wnt pathway is most frequently mutated in colorectal cancer. Previous studies have indicated that there is a crosstalk...
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Format: | Others |
Language: | English |
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Linköpings universitet, Institutionen för fysik, kemi och biologi
2009
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Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-18443 |