Human testis angiotensin-converting enzyme: Crystal structure of a glycosylation mutant and investigation of a putative hinge-mechanism by normal mode analysis.
Human angiotensin-converting enzyme (ACE) is a key enzyme in the regulation of blood pressure via the renin-angiotensin and kallikrein-kinin systems. A number of orally active drugs have been developed over the years that target somatic ACE, for the treatment of hypertension, myocardial infarction a...
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Format: | Others |
Language: | English |
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2004
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Online Access: | http://etd.uwc.ac.za/index.php?module=etd& |