Light-Induced Relocalization of the Photoreceptor G Protein Transducin is Mediated by Binding Partner-Restricted Diffusion: New Insights into G Protein Subunit Dissociation

Phototransduction is a well characterized system for study of G protein coupled receptor (GPCR) signaling. The GPCR rhodopsin couples to the heterotrimeric G protein transducin. Light-stimulated activation of transducin in turn activates phosphodiesterase (PDE), leading to closure to cGMP-gated chan...

Full description

Bibliographic Details
Main Author: Rosenzweig, Derek Hadar
Format: Others
Published: Scholarly Repository 2008
Subjects:
Online Access:http://scholarlyrepository.miami.edu/oa_dissertations/172