Characterizing the Heavy Metal Chelator, Tpen, as a Ca2+ Tool in the Mammalian Oocyte
N,N,N’,N’-tetrakis-(2-Pyridylmethyl) ethylenediamine (TPEN) is a heavy metal chelator with high affinity for zinc. TPEN causes important responses in mammalian eggs. For example, these eggs are arrested at the MII stage by the Endogenous Mitotic Inhibitor 2 (Emi2), which prevents activation of the A...
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| Format: | Others |
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ScholarWorks@UMass Amherst
2013
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| Online Access: | https://scholarworks.umass.edu/theses/1009 https://scholarworks.umass.edu/cgi/viewcontent.cgi?article=2097&context=theses |