Identification of Dynein Binding Sites in Budding Yeast Pac1/LIS1
Pac1/LIS1, an essential tip tracking protein of the WD40 super family, is required to target cytoplasmic dynein to the plus ends of astral microtubules in budding yeast. Pac1/LIS1 protein is composed of two regions: a small coiled-coil domain and a highly conserved WD40 repeat domain. Because of in...
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ScholarWorks@UMass Amherst
2010
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| Online Access: | https://scholarworks.umass.edu/theses/452 https://scholarworks.umass.edu/cgi/viewcontent.cgi?article=1537&context=theses |