Modulation of Notch in an Animal Model of Multiple Sclerosis

Multiple Sclerosis (MS) is a neurodegenerative autoimmune disease that affects millions of people worldwide. Although the exact cause of MS is unknown, it is clear that CD4+ T helper cells play a significant role, namely T helper 1 (Th1) and T helper 17 (Th17) cells. The Notch family of proteins pla...

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Bibliographic Details
Main Author: Munshi, Manit Nikhil
Format: Others
Published: ScholarWorks@UMass Amherst 2016
Subjects:
Th1
Th2
EAE
MOG
EPS
Online Access:https://scholarworks.umass.edu/masters_theses_2/437
https://scholarworks.umass.edu/cgi/viewcontent.cgi?article=1482&context=masters_theses_2