Calcium buffer incorporation reversibly inhibits DNA synthesis, nuclear envelope breakdown, and cell division in transformed keratinocytes

Loss of regulation of cell cycle events mediated by changes in cytosolic Ca$\sp{2+}$ ion activity has been implicated in the progression of normal cells to neoplasia. In this study, the Ca$\sp{2+}$ buffer 5,5$\sp\prime$-difluoro 1,2-bis(2-aminophenoxy) ethane-N,N,N$\sp\prime N\sp\prime$-tetra-acetic...

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Bibliographic Details
Main Author: Cishek, Dawn M
Language:ENG
Published: ScholarWorks@UMass Amherst 1996
Subjects:
Online Access:https://scholarworks.umass.edu/dissertations/AAI9638947