Identification of essential amino acids in the Cu(A) binding domain: Site directed mutagenesis in subunit II of cytochrome c oxidase of Saccharomyces cerevisiae

The Cu$\rm\sb{A}$ center, located in subunit II of cytochrome c oxidase, is the primary site for electron entry from cytochrome c. The recent crystal structure confirms this site to be a binuclear copper center with a dithiolate, dihistidyl coordination. A methionine and the carbonyl oxygen of Glu$\...

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Bibliographic Details
Main Author: Speno, Henry Salvatore
Language:ENG
Published: ScholarWorks@UMass Amherst 1996
Subjects:
Online Access:https://scholarworks.umass.edu/dissertations/AAI9619441