The role of Notch in Th17 differentation
Th17 cells are pro-inflammatory cells that are characterized by the production of their signature cytokine, IL-17. Although they are thought to have arisen to protect against extracellular bacteria and fungi they have been shown to mediate autoimmune diseases such as EAE and psoriasis. Notch protein...
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| Language: | ENG |
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ScholarWorks@UMass Amherst
2013
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| Online Access: | https://scholarworks.umass.edu/dissertations/AAI3603281 |