Tools for probing protein higher-order structure: Monitoring aggregation with native ESI-MS and conformational dynamics with top-down h/d exchange MS
The ability to monitor protein aggregation at the molecular level is critical for progress in many areas of life sciences ranging from exploring mechanisms of amyloidosis and etiology of conformational diseases to development of safe and efficient biopharmaceutical products. Despite the spectacular...
| Main Author: | |
|---|---|
| Language: | ENG |
| Published: |
ScholarWorks@UMass Amherst
2013
|
| Subjects: | |
| Online Access: | https://scholarworks.umass.edu/dissertations/AAI3603173 |