The viroporin activity of VP2, VP3 and VP4 contribute to the SV40 viral life cycle

Viruses have evolved to exploit cellular pathways and machinery in order to deliver their genome to the cell, replicate, and produce viral progeny. Nonenveloped viruses must overcome membrane barriers to infect host cells and trigger lysis for virion release. The model nonenveloped virus, Simian Vir...

Full description

Bibliographic Details
Main Author: Giorda, Kristina M
Language:ENG
Published: ScholarWorks@UMass Amherst 2012
Subjects:
Online Access:https://scholarworks.umass.edu/dissertations/AAI3545927