Microtechnologies for mimicking tumor-imposed transport limitations and developing targeted cancer therapies
Intravenously delivered cancer drugs face transport limitations at the tumor site and cannot reach all parts of tumors at therapeutically effective concentrations. Transport limitations also prevent oxygen from distributing evenly in tumors resulting in hypoxia, which plays a critical role in cancer...
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| Language: | ENG |
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ScholarWorks@UMass Amherst
2012
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| Online Access: | https://scholarworks.umass.edu/dissertations/AAI3498412 |