Regulation of mammary stem/progenitor cells by p53 and parity
Breast cancer is the most common tumor among women with inherited mutations in the p53 gene (Li-Fraumeni syndrome). The tumors represent the basal-like subtype which has been suggested to originate from mammary stem/progenitor cells. In mouse mammary epithelium, mammosphere-forming potential was inc...
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| Language: | ENG |
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ScholarWorks@UMass Amherst
2011
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| Online Access: | https://scholarworks.umass.edu/dissertations/AAI3482666 |