The role of Runx1 N-terminal splice isoforms in hematopoietic development
Runx1/AML1 transcription factor expression in hematopoietic cell lineages is differentially regulated via usage of two distinct promoters. The 5' UTR and a 19 amino acid encoding sequence transcribed from the distal promoter is inserted via alternative splicing into the 5' end of the mRNA...
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| Language: | ENG |
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ScholarWorks@UMass Amherst
2010
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| Online Access: | https://scholarworks.umass.edu/dissertations/AAI3397705 |