Determinants of stability in initiating and elongating T7 RNA polymerase complexes

Single subunit T7 RNA polymerase is relatively small and shares mechanistic features with all RNA polymerases, making it an ideal model to study transcription. The T7 RNA polymerase recognizes and binds specifically to a unique sequence in the DNA, melts the DNA at the start site and initiates de no...

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Bibliographic Details
Main Author: Liu, Xiaoqing
Language:ENG
Published: ScholarWorks@UMass Amherst 2009
Subjects:
Online Access:https://scholarworks.umass.edu/dissertations/AAI3379982