Intracellular metabolism of cancer cells and drug delivery using gold nanoparticles in an in vitro 3D tumor model
Heterogeneous tumor microenvironments reduce the efficacy of cancer therapeutics because associated heterogeneous tumor cell populations respond differently to treatments. Tumor cells develop altered metabolism to meet the increased energy demand for rapid proliferation and cell survival in unfavora...
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| Language: | ENG |
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ScholarWorks@UMass Amherst
2009
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| Online Access: | https://scholarworks.umass.edu/dissertations/AAI3359901 |