The role of ovarian hormones in p53-mediated resistance to mammary tumorigenesis
A full term pregnancy reduces breast cancer by up to 50%. In rodents, pregnancy or treatment with estrogen and progesterone to mimic pregnancy reduces mammary tumor incidence. The molecular mechanisms for parity-induced resistance to mammary tumorigenesis appear to involve a sustained increase in p5...
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| Language: | ENG |
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ScholarWorks@UMass Amherst
2008
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| Online Access: | https://scholarworks.umass.edu/dissertations/AAI3322194 |