Behavioral, physiological, and molecular mechanisms underlying reduced fertility in Nhlh2 knockout mice

Successful reproduction in mammals requires the interaction of the reproductive and neuroendocrine systems. Nhlh2 is a basic helix-loop-helix transcription factor that is expressed in both the developing and adult neuroendocrine hypothalamus. Targeted deletion (N2KO) of Nhlh2 results in hypogonadism...

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Bibliographic Details
Main Author: Johnson, Sarah A
Language:ENG
Published: ScholarWorks@UMass Amherst 2005
Subjects:
Online Access:https://scholarworks.umass.edu/dissertations/AAI3163678