Expanding the scope of templated macromolecular synthesis in vivo: The incorporation of methionine analogues into proteins in vivo by altering the methionyl-tRNA synthetase activity of a bacterial expression host
The incorporation of non-natural amino acids is an important strategy for engineering novel chemical and physical properties into natural and artificial proteins. The in vivo incorporation of non-natural amino acids is controlled by the aminoacyl-tRNA synthetases (aaRS), the class of enzymes that ca...
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| Language: | ENG |
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ScholarWorks@UMass Amherst
2001
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| Online Access: | https://scholarworks.umass.edu/dissertations/AAI3012149 |