Investigating the use of polyglutamic acid for enteric delivery of idiotypic antibodies

The success of an oral vaccine depends upon the ability of the antigen to target the Peyer's Patches of the small intestine, uptake and presentation of the antigen to local immune effector cells, and the antigenicity of the antigen. Most proteins are poor mucosal immunogens and therefore have b...

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Bibliographic Details
Main Author: Blanchard, Thomas Gerod
Language:ENG
Published: ScholarWorks@UMass Amherst 1991
Subjects:
Online Access:https://scholarworks.umass.edu/dissertations/AAI9132821