Structure elucidation of natural products from endophytic fungi and higher plants and total synthesis of microcarpalide
Part-1: Microcarpalide (1.1), a new alkyl-substituted nonenolide was isolated from fermentation broths of an unidentified fungus. Microcarpalide is weakly cytotoxic to mammalian cells and acts as a microfilament disrupting agent. The gross structure of 1.1 was elucidated by the application of spectr...
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University of Hawaii at Manoa
2009
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Online Access: | http://hdl.handle.net/10125/6907 |