Structure elucidation of natural products from endophytic fungi and higher plants and total synthesis of microcarpalide

Part-1: Microcarpalide (1.1), a new alkyl-substituted nonenolide was isolated from fermentation broths of an unidentified fungus. Microcarpalide is weakly cytotoxic to mammalian cells and acts as a microfilament disrupting agent. The gross structure of 1.1 was elucidated by the application of spectr...

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Bibliographic Details
Main Author: Ratnayake, Anokha Sayani
Other Authors: Hemscheidt, Thomas K
Published: University of Hawaii at Manoa 2009
Online Access:http://hdl.handle.net/10125/6907