The role of caspases in lytic mechanisms of tumor necrosis factor-mediated cytolysis
TNF activates several signaling pathways, some lead to cell death by apoptosis or necrosis. For our cell lines (B/C-N, 10ME, and L88.3), which represent a tumor progression model, it has not been determined whether TNF induces apoptosis or necrosis. B/C-N is not tumorigenic and represents normal cel...
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Language: | en-US |
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University of Hawaii at Manoa
2008
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Online Access: | http://hdl.handle.net/10125/3008 |