The role of caspases in lytic mechanisms of tumor necrosis factor-mediated cytolysis

TNF activates several signaling pathways, some lead to cell death by apoptosis or necrosis. For our cell lines (B/C-N, 10ME, and L88.3), which represent a tumor progression model, it has not been determined whether TNF induces apoptosis or necrosis. B/C-N is not tumorigenic and represents normal cel...

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Bibliographic Details
Main Author: Chang, Wei-Chuan
Other Authors: Patek, Paul Q
Language:en-US
Published: University of Hawaii at Manoa 2008
Online Access:http://hdl.handle.net/10125/3008