Statin-induced muscle mitochondrial toxicity

Statins are the mainstay of cholesterol-lowering therapy and are taken by millions of people worldwide. These drugs are generally well-tolerated but can cause myopathy ranging from mild muscle pain to fatal rhabdomyolysis. The mechanism of statin-induced myopathy (SIM) is not fully understood and th...

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Bibliographic Details
Main Author: Schick, Brian Adam
Format: Others
Language:English
Published: University of British Columbia 2008
Subjects:
Online Access:http://hdl.handle.net/2429/908