Idiosyncratic valproic acid-induced hepatotoxicity : an in vitro approach to detection and mechanism of toxicity

Idiosyncratic valproic acid-induced hepatotoxicity : an in vitro approach to detection and mechanism of toxicity

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The first objective of this study was to develop a rapid, high capacity, and objective in vitro cytotoxicity method for the detection of metabolism-dependent cytotoxicity of a test chemical. The in vitro system uses an external biotransformation system (rabbit liver microsomes plus NADPH) in conj...

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Bibliographic Details
Main Author:	Tabatabaei, Ali Reza
Format:	Others
Language:	English
Published:	2009
Online Access:	http://hdl.handle.net/2429/8648

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