Idiosyncratic valproic acid-induced hepatotoxicity : an in vitro approach to detection and mechanism of toxicity
The first objective of this study was to develop a rapid, high capacity, and objective in vitro cytotoxicity method for the detection of metabolism-dependent cytotoxicity of a test chemical. The in vitro system uses an external biotransformation system (rabbit liver microsomes plus NADPH) in conj...
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| Format: | Others |
| Language: | English |
| Published: |
2009
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| Online Access: | http://hdl.handle.net/2429/8648 |