Regulation of amyloid precursor protein catabolism in vitro : the role of mitogen-activited protein kinase and protein kinase C
Secretory processing of the amyloid precursor protein (APP) generating soluble APP fragments occurs via two routes broadly categorized as non-amyloidogenic (yielding a truncated APP derivative known as APPS) or potentially amyloidogenic (yielding intact Aβ). These catabolic pathways are mutually...
Main Author: | |
---|---|
Format: | Others |
Language: | English |
Published: |
2009
|
Online Access: | http://hdl.handle.net/2429/8415 |