Regulation of amyloid precursor protein catabolism in vitro : the role of mitogen-activited protein kinase and protein kinase C

Secretory processing of the amyloid precursor protein (APP) generating soluble APP fragments occurs via two routes broadly categorized as non-amyloidogenic (yielding a truncated APP derivative known as APPS) or potentially amyloidogenic (yielding intact Aβ). These catabolic pathways are mutually...

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Bibliographic Details
Main Author: Mills, Julia
Format: Others
Language:English
Published: 2009
Online Access:http://hdl.handle.net/2429/8415