Mapping complex genomic translocations using Strand-seq
Template strand sequencing (Strand-seq) is a single cell sequencing approach which maintains 5’ -> 3’ directionality of sequence reads. I hypothesized that the directional information preserved can be used to map complex translocation events. Translocations often disrupt gene expression by reshuf...
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| Language: | English |
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University of British Columbia
2018
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| Online Access: | http://hdl.handle.net/2429/64226 |