The establishment of a flow cytometry system to study HTT regulation and expression
Huntington’s disease (HD) is a late-onset neurodegenerative disorder characterized by motor deficits, behavioral abnormalities and psychiatric symptoms. HD is caused by a CAG trinucleotide repeat expansion in the HTT gene resulting in expression of a mutant polyglutamine stretch in the huntingtin pr...
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| Language: | English |
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University of British Columbia
2017
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| Online Access: | http://hdl.handle.net/2429/62917 |