Comprehensive and integrative analysis of the KMT2D regulome

Lysine (K)-specific methyltransferase 2D (KMT2D) is a critical component of epigenetic regulation through its role in mono-methylation of lysine 4 of histone H3 (H3K4me1). KMT2D is among the most frequently mutated genes in many forms of cancer, with particularly high occurrence of mutation in lymph...

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Bibliographic Details
Main Author: Topham, James T.
Language:English
Published: University of British Columbia 2017
Online Access:http://hdl.handle.net/2429/62438