Antibiotic inhibition of catalytic RNA function

A number of compounds inhibit group I intron splicing. Competitive inhibitors include deoxyguanosine, dideoxyguanosine, arginine and streptomycin; the non-competitive inhibitors include members of the aminoglycoside family of antibiotics. Further screening of a collection of antibiotics for their...

Full description

Bibliographic Details
Main Author: Rogers, Jeff
Format: Others
Language:English
Published: 2009
Online Access:http://hdl.handle.net/2429/6141