Pharmacokinetics, biodistribution and intratumoral distribution of Celludo nanoparticles

Anti-tubulin agents are the most potent and broadest spectrum drugs for cancer therapy, including taxanes and vinca alkaloids. However, there are two major limitations for their clinical use: multidrug resistance (MDR), and significant side effects such as neutropenia and neuropathy. The overexpress...

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Bibliographic Details
Main Author: Zhao, Yucheng
Language:English
Published: University of British Columbia 2016
Online Access:http://hdl.handle.net/2429/59454