LRRK2 and the p.G2019S mutation in neuronal and systemic response to induced α-synuclein pathobiology
Parkinson’s disease (PD) is a progressive neurodegenerative disorder for which no disease-modifying treatments are currently available. PD is neuropathologically characterized by selective degeneration of nigral dopaminergic neurons and the presence of intraneuronal inclusions comprised primarily of...
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Language: | English |
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University of British Columbia
2016
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Online Access: | http://hdl.handle.net/2429/58667 |