LRRK2 and the p.G2019S mutation in neuronal and systemic response to induced α-synuclein pathobiology

Parkinson’s disease (PD) is a progressive neurodegenerative disorder for which no disease-modifying treatments are currently available. PD is neuropathologically characterized by selective degeneration of nigral dopaminergic neurons and the presence of intraneuronal inclusions comprised primarily of...

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Bibliographic Details
Main Author: MacIsaac, Sarah
Language:English
Published: University of British Columbia 2016
Online Access:http://hdl.handle.net/2429/58667