Assessment of the onset and progress of apoptosis via Raman spectroscopy

Apoptotic and necrotic cell death is ultimately the cause of productivity loss in bioreactors used to produce therapeutic proteins. This study investigates the suitability of Raman spectroscopy to detect the onset and types of cell death in Chinese Hamster Ovary (CHO) cells - the most widely used ce...

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Bibliographic Details
Main Author: Rangan, Shreyas
Language:English
Published: University of British Columbia 2016
Online Access:http://hdl.handle.net/2429/57891