Roles of Mediator subunit CDK-8 in developmental and physiological responses in Caenorhabditis elegans

The Mediator complex is a conserved coregulator of RNA polymerase II transcription. Whereas some Mediator subunits are universally essential for transcription, others regulate specialized gene programs by interacting with sequence-specific transcription factors (TFs). Mediator’s Cyclin dependent kin...

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Bibliographic Details
Main Author: Grants, Jennifer M.
Language:English
Published: University of British Columbia 2016
Online Access:http://hdl.handle.net/2429/57855