A pursuit of sequence specific RNase A mimicking DNAzymes

DNAzymes are single-stranded DNA molecules capable of catalysis, and they are the DNA counterparts of ribozymes and protein enzymes. M²⁺-independent RNA cleaving DNAzymes are intriguing due to their robust activity that is not compromised by low Mg²⁺ that is found in cells. Hence, they hold great pr...

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Bibliographic Details
Main Author: Wang, Yajun
Language:English
Published: University of British Columbia 2016
Online Access:http://hdl.handle.net/2429/57689