Searching for inhibitors of the protein arginine methyl transferases : synthesis and characterisation of peptidomimetic ligands

Within the last two decades research in the field of epigenetics has increased significantly as targeting the epigenetic enzymes has the potential to alter the transcription of genes. Aberrant regulation of transcription is seen in several disease states, and drugs targeting the epigenetic histone d...

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Bibliographic Details
Main Author: Knuhtsen, Astrid
Language:English
Published: University of British Columbia 2016
Online Access:http://hdl.handle.net/2429/57228