Single-cell analysis of hematopoietic stem cell identity and behaviour

The concept of stem cell self-renewal was developed from clonal tracking of hematopoietic stem cell (HSC) divisions in vivo 50 years ago. However, protocols to expand these cells in vitro without loss of their stem cell properties have remained elusive. A number of factors contribute to this inabili...

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Bibliographic Details
Main Author: Knapp, David Jorg Hans Fraser
Language:English
Published: University of British Columbia 2015
Online Access:http://hdl.handle.net/2429/55875