Transcriptional silencing of endogenous retroviruses by the novel lysine methyltransferase co-repressor hnRNP K

Histone lysine methylation is essential for mammalian development and maintenance of somatic cell identity, as evidenced by a group of Mendelian diseases and cancers linked with mutations in lysine methyltransferases (KMTs). The transcriptional silencing of a class of retrotransposons known as endog...

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Bibliographic Details
Main Author: Thompson, Peter Jeffrey
Language:English
Published: University of British Columbia 2015
Online Access:http://hdl.handle.net/2429/55760