Transcriptional silencing of endogenous retroviruses by the novel lysine methyltransferase co-repressor hnRNP K
Histone lysine methylation is essential for mammalian development and maintenance of somatic cell identity, as evidenced by a group of Mendelian diseases and cancers linked with mutations in lysine methyltransferases (KMTs). The transcriptional silencing of a class of retrotransposons known as endog...
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Language: | English |
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University of British Columbia
2015
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Online Access: | http://hdl.handle.net/2429/55760 |