Intestinal microbiota contributes to the pathogenesis of type 1 diabetes in the non-obese diabetic mouse

Accumulating evidence supports the idea that intestinal microbes are involved in the pathogenesis of type 1 diabetes (T1D) through the gut-pancreas nexus. While it has been hypothesized that a “leaky” gut could facilitate exposure to microbial antigens and accelerate diabetes onset, the role of the...

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Bibliographic Details
Main Author: Brown, Kirsty
Language:English
Published: University of British Columbia 2015
Online Access:http://hdl.handle.net/2429/55013