The search for novel inhibitors of coactivator-associated arginine methyltransferase 1

Coactivator-associated arginine methyltransferase 1 (CARM1) is a member of the protein arginine methyltransferase (PRMT) family of enzymes, and is also known as PRMT4. PRMTs catalyse the transfer of methyl groups from S-adenosyl-L-methionine (SAM) to the side chain of arginine residues in substrate...

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Bibliographic Details
Main Author: Sedlock, Shona Anne
Language:English
Published: University of British Columbia 2015
Online Access:http://hdl.handle.net/2429/54583