Functional characterization of sex hormone-binding globulin genetic polymorphism

Human plasma SHBG is produced by the liver, and it transports biologically active sex steroids and determines their availability to target tissues. The 4.3 kb human SHBG transcriptional unit encoding a signal polypeptide for secretion followed by two laminin G (LG)-like domains is utilized by hepato...

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Bibliographic Details
Main Author: Wu, Tsung-Sheng
Language:English
Published: University of British Columbia 2015
Online Access:http://hdl.handle.net/2429/53980