Functional studies of PPP2R2A in breast cancer
PPP2R2A is a regulatory subunit of protein phosphatase 2A (PP2A). Genomic analysis based on 2000 breast cancer cases identified PPP2R2A as one of the deletion hotspots in breast cancer genomes and 63% of PPP2R2A deletions were found in estrogen receptor positive (ER+) breast cancers. We hypothesized...
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| Language: | English |
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University of British Columbia
2015
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| Online Access: | http://hdl.handle.net/2429/52922 |