PPP2R1A mutations in gynaecologic cancers: functional characterization and use in the genomic classification of tumours

Endometrial carcinoma is the most common gynaecological cancer in developed countries. The current endometrial pathologic classification system lacks reproducibility, which has hampered the development of new treatments for these cancers. The PP2A phosphatase complexes are responsible for regulating...

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Bibliographic Details
Main Author: McConechy, Melissa
Language:English
Published: University of British Columbia 2015
Online Access:http://hdl.handle.net/2429/52829