Intracellular trafficking of a model polytopic membrane protein in Saccharomyces cerevisiae

Polytopic membrane protein synthesis involves translation followed by translocation across the lipid bilayer at the ER. Here, various chaperones, together with enzymes that add post and co-translational modifications, help the protein achieve a final three-dimensional structure. General and substrat...

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Bibliographic Details
Main Author: Dharwada, Sai Tejasvi
Language:English
Published: University of British Columbia 2015
Online Access:http://hdl.handle.net/2429/52727