Valvular interstitial cell transformation : implications for aortic valve calcification

Aortic valve stenosis (AVS) involves the transformation of valvular interstitial cells (VIC) into an osteoblastic phenotype. Such valvular disease is mostly associated with both thickening and calcification of the valve cusps, which is accompanied by inflammation and remodeling of the tissue. This p...

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Bibliographic Details
Main Author: Boroomand, Seti
Language:English
Published: University of British Columbia 2014
Online Access:http://hdl.handle.net/2429/47138