Contribution of p-glycoprotein mediated-efflux to the epithelial transport of amphotericin b in caco-2 cells
Background: Amphotericin B (AmB) is a highly efficacious therapeutic for invasive fungal infections (IFIs) and protozoal diseases. Increasing prevalence of these conditions necessitates the development of an oral AmB formulation, with reduced toxicity, improved tissue distribution, and improved affo...
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| Language: | English |
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University of British Columbia
2014
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| Online Access: | http://hdl.handle.net/2429/46529 |